3D Bioplotter Research Papers

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Displaying all papers by J. Asami (1 results)

Meniscal repair with additive manufacture of bioresorbable polymer: From physicochemical characterization to implantation of 3D printed poly (L-co-D, L lactide-co-trimethylene carbonate) with autologous stem cells in rabbit

Journal of Biomaterials Applications 2024 Volume 39, Issue 1, Pages 66-79

Authors:D. Komatsu A. R. E. Cabrera B. V. Quevedo J. Asami A. C. Motta S. C. de Moraes M. A. T. Duarte M. A. Hausen E. A. R. Duek

Three-dimensional (3D) structures are actually the state-of-the-art technique to create porous scaffolds for tissue engineering. Since regeneration in cartilage tissue is limited due to intrinsic cellular properties this study aims to develop and characterize three-dimensional porous scaffolds of poly (L-co-D, L lactide-co-trimethylene carbonate), PLDLA-TMC, obtained by 3D fiber deposition technique. The PLDLA-TMC terpolymer scaffolds (70:30), were obtained and characterized by scanning electron microscopy, gel permeation chromatography, differential scanning calorimetry, thermal gravimetric analysis, compression mechanical testing and study on in vitro degradation, which showed its amorphous characteristics, cylindrical geometry, and interconnected pores. The in vitro degradation study showed significant loss of…

Keywords:PLDLA-TMC Mesenchymal stem cells (MSCs) in-vivo (rabbit) Meniscus Cartilage Regeneration