3D Bioplotter Research Papers

3D printing enables precise control over tablet design and drug release, but challenges remain in optimising ink formulation, ensuring printability, and predicting final tablet properties. This study addresses the need for data-driven strategies in fabricating chewable tablets and tests the hypothesis that integrating rheology with machine learning (ML) enables predictive control over print quality and dosage form performance. We developed drug nanosuspension inks with varying water content (85–20 wt.%) and identified 40% as optimal, balancing shear-thinning behaviour, yield stress, and shear recovery for consistent extrusion. Analytical models predicted strut diameter (D) based on printing parameters—pressure (P), speed (v), and nozzle…

Polymeric systems displaying spontaneous formation of surface wrinkling patterns are useful for a wide range of applications, such as diffraction gratings, flexible electronics, smart adhesives, optical devices, and cell culture platforms. Conventional fabrication techniques for wrinkling patterns involves multitude of processing steps and impose significant limitations on fabrication of hierarchical patterns, creating wrinkles on 3D and nonplanar structures, the scalability of the manufacturing process, and the integration of wrinkle fabrication process into a continuous manufacturing process. In this work, 4D printing of surface morphing hydrogels enabling direct fabrication of wrinkling patterns on curved and/or 3D structures with user-defined and spatially…