3D Bioplotter Research Papers

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Displaying all papers by A. O. Pires (1 results)

Interactions between Schwann and olfactory ensheathing cells with a starch/polycaprolactone scaffold aimed at spinal cord injury repair

Journal of Biomedical Materials Research Part A 2012 Volume 100A, Issue 2, Pages 470-476

Authors:N. A. Silva R. A. Sousa A. O. Pires N. Sousa A. J. Salgado R. L. Reis

Spinal cord injury (SCI) represents a major world health problem. Therefore it is urgent to develop novel strategies that can specifically target it. We have previously shown that the implantation of starch-based scaffolds (SPCL) aimed for spine stabilization on SCI animals leads to motor skills improvements. Therefore, we hypothesize that the combination of these scaffolds with relevant cell populations for SCI repair will, most likely, lead to further improvements. Therefore, in this work, the ability of SPCL scaffolds to support the 3D culture of olfactory ensheathing cells (OECs) and Schwann cells (SCs) was studied and characterized. The results demonstrate for…

Keywords:Coating (Poly-L-lysine) in-vitro Olfactory ensheathing cells Schwann Cells SPCL