™
3D Bioplotter Research Papers
Displaying all papers by G. Gao (1 results)
3D-printed regenerative polycaprolactone/silk fibroin osteogenic and chondrogenic implant for treatment of hip dysplasia
Biochemical and Biophysical Research Communications
2022
Volume 636, Part 1, Pages 96-104
Hip dysplasia is a developmental disorder that resulted in insufficient acetabular coverage. Current surgical treatments are technically demanding, complex, invasive, and often lead to associated complications. Therefore, the development of regenerative implants that fit to the bone and induce osteogenesis and chondrogenesis is in high demand. In this study, an implant was developed in which the osteogenic part was 3D printed using polycaprolactone (PCL), crosslinked with dopamine, and subjected to surface mineralization; while the chondrogenic part was prepared using silk fibroin (SF) and bone morphogenetic protein 2. Physical and chemical characterization of the implant was conducted using energy dispersive spectrometry…