3D Bioplotter Research Papers

Purpose: The repair effect of peripheral nerve injury mainly depends on rapid regeneration of proximal axons, accurate docking, and effective nerve re-innervation of target organs. Accordingly, identifying effective methods to protect the functional state of target organs and realize rapid regeneration of proximal nerve fibers is of great significance. The purpose of this study is to build a nervous electrical stimulation system powered by electromagnetic induction and evaluate its repair effect on a rat sciatic nerve defect model. Methods: Biodegradable materials [magnesium (Mg), polylactic acid (PLLA), chitosan, and silk fibroin] were chosen to build thein vivo part of the wireless…

3D printing provides a novel approach to repair bone defects using customized biomimetic tissue scaffolds. To make a bone substitute closest to natural bone structure and composition, two different types of hydroxyapatite, Nano hydroxyapatite (nHA) and deproteinized bovine bone (DBB), were dispersed into collagen (CoL) to prepare the bio-ink for 3D printing. In doing so, a porous architecture was manufactured with 3D printing technology. The physical and chemical properties of the materials were evaluated, including biocompatibility and effect on the osteogenic differentiation of the human bone marrow-derived mesenchyme stem cells (hBMSCs). The XPS, XRD, FTIR, and the mechanical analysis of…