™
3D Bioplotter Research Papers
Displaying all papers by P. Lyu (1 results)
Hydroxyapatite /Collagen 3D printed Scaffolds and their Osteogenic Effects on hBMSCs
Tissue Engineering Part A
2019
Volume: 25 Issue 17-18, Pages 1261-1271
3D printing provides a novel approach to repair bone defects using customized biomimetic tissue scaffolds. To make a bone substitute closest to natural bone structure and composition, two different types of hydroxyapatite, Nano hydroxyapatite (nHA) and deproteinized bovine bone (DBB), were dispersed into collagen (CoL) to prepare the bio-ink for 3D printing. In doing so, a porous architecture was manufactured with 3D printing technology. The physical and chemical properties of the materials were evaluated, including biocompatibility and effect on the osteogenic differentiation of the human bone marrow-derived mesenchyme stem cells (hBMSCs). The XPS, XRD, FTIR, and the mechanical analysis of…