3D Bioplotter Research Papers

3D-printing paves the way for personalized drug therapy via implants individualized for the patient specific anatomy in chronic paranasal sinus diseases. This study brings together the workflow of modeling, manufacturing, and sterilization of 3D-printed individualized frontal neo-ostium implants (FOI) for optimization of Endoscopic Sinus Surgery (ESS) and validates the implantability of the printed devices. The study sample consisted of six adult human cadavers. Digital volume tomography (DVT) images were taken before and after ESS. The FOI models were based on the post-ESS anatomy. The area to be implanted was analysed in the preand post-ESS DVT images for volume and surface…

The aim of this study was to develop and validate a semi-automated segmentation approach that identifies the round window niche (RWN) and round window membrane (RWM) for use in the development of patient individualized round window niche implants (RNI) to treat inner ear disorders. Twenty cone beam computed tomography (CBCT) datasets of unilateral temporal bones of patients were included in the study. Defined anatomical landmarks such as the RWM were used to develop a customized 3D Slicer™ plugin for semi-automated segmentation of the RWN. Two otolaryngologists (User 1 and User 2) segmented the datasets manually and semi-automatically using the developed…