3D Bioplotter Research Papers
Displaying all papers by Y. Mao (1 results)
A method to deliver patterned electrical impulses to Schwann cells cultured on an artificial axon
Neural Regeneration Research
2019
Volume 14, Issue 6, Pages 1052-1059
Information from the brain travels back and forth along peripheral nerves in the form of electrical impulses generated by neurons and these impulses have repetitive patterns. Schwann cells in peripheral nerves receive molecular signals from axons to coordinate the process of myelination. There is evidence, however, that non-molecular signals play an important role in myelination in the form of patterned electrical impulses generated by neuronal activity. The role of patterned electrical impulses has been investigated in the literature using co-cultures of neurons and myelinating cells. The co-culturing method, however, prevents the uncoupling of the direct effect of patterned electrical impulses…