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3D Bioplotter Research Papers
Displaying all papers by Y. Ucar (1 results)
A biomimetic growth factor delivery strategy for enhanced regeneration of iliac crest defects
Biomedical Materials
2013
Volume 8, Number 4, 045009
The importance of provision of growth factors in the engineering of tissues has long been shown to control the behavior of the cells within the construct and several approaches were applied toward this end. In nature, more than one type of growth factor is known to be effective during the healing of tissue defects and their peak concentrations are not always simultaneous. One of the most recent strategies includes the delivery of a combination of growth factors with the dose and timing to mimic the natural regeneration cascade. The sequential delivery of bone morphogenetic proteins BMP-2 and BMP-7 which are…