3D Bioplotter Research Papers

Displaying all papers about Dental Papilla Cells (DPCs) (1 results)

3D-bioprinted Recombination Structure of Hertwig’s Epithelial Root Sheath Cells and Dental Papilla Cells for Alveolar Bone Regeneration

International Journal of Bioprinting 2022 Volume 8, Issue 3, Article 512

Three-dimensional (3D) bioprinting is an emerging method for tissue regeneration. However, promoting the epithelial-mesenchymal interaction (EMI), while maintaining the characteristics of epithelial cells has always been a challenge in tissue engineering. Since EMI acts as a critical factor in bone regeneration, this study aims to promote EMI by recombining epithelial and mesenchymal cells through 3D bioprinting. Hertwig’s epithelial root sheath (HERS) is a transient structure appeared in the process of tooth root formation. Its epithelial characteristics are easy to attenuate under appropriate culture environment. We recombined HERS cells and dental papilla cells (DPCs) through 3D bioprinting to simulate the microenvironment…