3D Bioplotter Research Papers

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Displaying all papers about Limbal Stem Cells (LSCs) (1 results)

3D Bioprinting of Human Cornea Mimicking Structures with Stroma and Epithelium

Tampere University 2023 Thesis

Authors:S. Huhtanen

“There is an immense need for corneal transplants to restore vision after injury or disease. Due to the shortage of donor corneas, three dimensional (3D) bioprinting has emerged as a possible solution to create cornea mimicking structures. The cornea consists of five layers, with the stroma and epithelium forming the two outermost cellular layers. To be able to 3D bioprint these layers, bioinks, and appropriate cell types are needed. For the epithelial layer, human pluripotent stem cell -derived corneal limbal epithelial stem cells (hPSC-LSCs) have great potential. For the stromal layer, human adipose stem cells -derived corneal stromal keratocytes (hASC-CSKs)…

Keywords:Dopamine-modified Carbodihydrazide-conjugated Hyaluronic Acid Collagen Hyaluronic Acid Hyaluronic Acid Aldehyde LAP Stromal Cells Adipose Derived Stem Cells (ADSC) Limbal Stem Cells (LSCs) Cell Printing in-vitro Cornea Repair Soft Tissue Regeneration