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3D Bioplotter Research Papers
Displaying all papers by J. K. Christie (1 results)
Multi-layer Scaffolds of Poly(caprolactone), Poly(glycerol sebacate) and Bioactive Glasses Manufactured by Combined 3D Printing and Electrospinning
nanomaterials
2020
Volume 10, Issue 4, Article 626
Three-dimensional (3D) printing has been combined with electrospinning to manufacture multi-layered polymer/glass scaffolds that possess multi-scale porosity, are mechanically robust, release bioactive compounds, degrade at a controlled rate and are biocompatible. Fibrous mats of poly (caprolactone) (PCL) and poly (glycerol sebacate) (PGS) have been directly electrospun on one side of 3D-printed grids of PCL-PGS blends containing bioactive glasses (BGs). The excellent adhesion between layers has resulted in composite scaffolds with a Young’s modulus of 240–310 MPa, higher than that of 3D-printed grids (125–280 MPa, without the electrospun layer). The scaffolds degraded in vitro by releasing PGS and BGs, reaching a…