3D Bioplotter Research Papers

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Displaying all papers by J. Kuschnierz (1 results)

Bone repair by cell-seeded 3D-bioplotted composite scaffolds made of collagen treated tricalciumphosphate or tricalciumphosphate-chitosan-collagen hydrogel or PLGA in ovine critical-sized calvarial defects

Journal of Biomedical Materials Research Part B: Applied Biomaterials 2010 Volume 93B, Issue 2, Pages 520-530
K. Haberstroh K. Ritter J. Kuschnierz K-H. Bormann C. Kaps C. Carvalho R. Mülhaupt M. Sittinger N-C. Gellrich

The aim of this study was to investigate the osteogenic effect of three different cell-seeded 3D-bioplotted scaffolds in a ovine calvarial critical-size defect model. The choice of scaffold-materials was based on their applicability for 3D-bioplotting and respective possibility to produce tailor-made scaffolds for the use in cranio-facial surgery for the replacement of complex shaped boneparts. Scaffold raw-materials are known to be osteoinductive when being cell-seeded [poly(L-lactide-co-glycolide) (PLGA)] or having components with osteoinductive properties as tricalciumphosphate (TCP) or collagen (Col) or chitosan. The scaffold-materials PLGA, TCP/Col, and HYDR (TCP/Col/chitosan) were cell-seeded with osteoblast-like cells whether gained from bone (OLB) or from…

Bone Regeneration Chitosan Coating (Collagen) Collagen Cranial Defects in-vivo (sheep) Osteoblast-like Cells PLGA Polyvinylalcohol Tricalcium Phosphate