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3D Bioplotter Research Papers
Displaying all papers by J. Rotmans (1 results)
Control Delivery of Multiple Growth Factors to Actively Steer Differentiation and Extracellular Matrix Protein Production
Advanced Biology
2021
Volume 5, Issue 4, Article 2000205
In tissue engineering, biomaterials have been used to steer the host response. This determines the outcome of tissue regeneration, which is modulated by multiple growth factors (GFs). Hence, a sustainable delivery system for GFs is necessary to control tissue regeneration actively. A delivery technique of single and multiple GF combinations, using a layer‐by‐layer (LBL) procedure to improve tissue remodeling, is developed. TGF‐β1, PDGF‐ββ, and IGF‐1 are incorporated on tailor‐made polymeric rods, which could be used as a tool for potential tissue engineering applications, such as templates to induce the formation of in situ tissue engineered blood vessels (TEBVs). Cell response…