3D Bioplotter Research Papers

Porcelain pastes (PlotPastes) were formulated to be used on an additive manufacturing (AM) process (material extrusion) process, primarily robocasting (R3D) technique. The material morphological and thermal characteristics were evaluated by scanning electron microscopy (SEM), differential thermal analysis (DTA) and thermogravimetric analysis (TGA). The rheology and the electrical potential of the ceramic particles were also studied to select and adequate the porcelain paste properties to the R3D AM technique. It was found that shifting the pH values to acidic, the surface charge of the particles changes and increases the pastes viscosity due to agglomeration effects. This behaviour was exploited to optimize…

3D bioprinting is a versatile technique that allows the fabrication of living tissue analogs through the layer-by-layer deposition of cell-laden biomaterials, viz. bioinks. In this work, composite alginate hydrogel-based bioinks reinforced with curcumin-loaded particles of cellulose esters (CEpCUR) and laden with human keratinocytes (HaCaT) are developed. The addition of the CEpCUR particles, with sizes of 740 ± 147 nm, improves the rheological properties of the inks, increasing their shear stress and viscosity, while preserving the recovery rate and the mechanical and viscoelastic properties of the resulting fully cross-linked hydrogels. Moreover, the presence of these particles reduces the degradation rate of…