3D Bioplotter Research Papers
Three-Dimensional-Bioprinted Bioactive Glass/Cellulose Composite Scaffolds with Porous Structure towards Bone Tissue Engineering
In this study, three-dimensional (3D) bioactive glass/lignocellulose (BG/cellulose) composite scaffolds were successfully fabricated by the 3D-bioprinting technique with N-methylmorpholine-N-oxide (NMMO) as the ink solvent. The physical structure, morphology, mechanical properties, hydroxyapatite growth and cell response to the prepared BG/cellulose scaffolds were investigated. Scanning electron microscopy (SEM) images showed that the BG/cellulose scaffolds had uniform macropores of less than 400 μm with very rough surfaces. Such BG/cellulose scaffolds have excellent mechanical performance to resist compressive force in comparison with pure cellulose scaffolds and satisfy the strength requirement of human trabecular bone (2-12 MPa). Furthermore, BG significantly increased the excellent hydroxyapatite-forming capability…