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3D Bioplotter Research Papers
Displaying all papers by Y. Zhuang (1 results)
Three-dimensional printing hydrogel scaffold with bioactivity and shape-adaptability for potential application in irregular bone defect regeneration
Journal of Applied Polymer Science
2022
Volume 139, Issue 35, Article e52831
Complex shaped bone defects that need to be filled are very common in clinic. But after filling, gaps are inevitably left between substitutes and host bone due to the poor conformability of preformed implants, hence hindering bone regeneration. Therefore, based on our previous study, we here used the bioink (named PPG) composed of polyurethane, polyacrylamide, and gelatin with optimized composition ratio to three-dimensionally (3D) print an inorganic/organic composite hydrogel scaffold with self-expandability to fill irregular bone defects and bioactivity to accelerate bone healing through adjusting the content of bioactive ceramic (BC). The results indicated that, the 3D printed BC/PPG scaffold…