3D Bioplotter Research Papers

Cultured meat is the solution to reduce resources used in traditional meat production. It helps produce meat without killing livestock and decrease unnecessary residue. This process requires three-dimensional scaffold for the cell attachment and the formation of artificial meat including natural textures. To achieve the goal of cultured meat, the scaffold material should not be derived from animal products as well. Therefore, this study aims to investigate mechanical properties, rheology, biocompatibility and cell attachment of 2% w/v alginate, 0.8% w/v agarose and 1.5% w/v carboxymethyl cellulose hydrogel. The structures of hydrogel were printed, and the suitable printing conditions were examined.…

Organ-on-a-chip stands as a pivotal platform for skeletal muscle research while constructing 3D skeletal muscle tissues that possess both macroscopic and microscopic structures remains a considerable challenge. This study draws inspiration from LEGO-like assembly, employing a modular approach to construct muscle tissue that integrates biomimetic macroscopic and microscopic structures. Modular LEGO-like hybrid nanofibrous scaffold bricks were fabricated by the combination of 3D printing and electrospinning techniques. Skeletal muscle cells cultured on these modular scaffold bricks exhibited a highly orientated nanofibrous structure. A variety of construction of skeletal muscle tissues further enabled development by various assembling processes. Moreover, skeletal muscle-on-a-chip (SMoC)…