3D Bioplotter Research Papers

Addressing critical-sized bone defects poses significant challenges due to the limitations of natural bone regeneration and conventional treatments like tissue transplantation. Bone tissue engineering and 3D bioprinting offer promising solutions by creating customized, biomimetic scaffolds. This study explores the innovative use of UiO-66 metal-organic framework (MOF) nanocrystals to enhance the osteoinductive and osteogenic properties of 3D bioprinted scaffolds. UiO-66 nanocrystals were synthesized and characterized, demonstrating uniform morphology and highly crystalline structure. These nanocrystals were then incorporated into alginate/methyl cellulose (AL/MC) hydrogel at various concentrations and print parameters were optimized based on physicochemical properties. AL/MC/UiO-66 optimized under specific conditions was then…

A key challenge towards engineering 3D printed soft tissues is the availability of proper scaffolding materials with enough load carrying capacity. In this study, we synthesized biocompatible and biodegradable, elastomeric polyurethaneureas (TPUU) and investigated the applicability of these novel materials as 3D printed load carrying constructs.