3D Bioplotter Research Papers
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Tuning thermoresponsive properties of carboxymethyl cellulose (CMC)–agarose composite bioinks to fabricate complex 3D constructs for regenerative medicine
International Journal of Biological Macromolecules
2024
Volume 260, Part 1, Article 129443
3D bioprinting has emerged as a viable tool to fabricate 3D tissue constructs with high precision using various bioinks which offer instantaneous gelation, shape fidelity, and cytocompatibility. Among various bioinks, cellulose is the most abundantly available natural polymer & widely used as bioink for 3D bioprinting applications. To mitigate the demanding crosslinking needs of cellulose, it is frequently chemically modified or blended with other polymers to develop stable hydrogels. In this study, we have developed a thermoresponsive, composite bioink using carboxymethyl cellulose (CMC) and agarose in different ratios (9:1, 8:2, 7:3, 6:4, and 5:5). Among the tested combinations, the 5:5…