3D Bioplotter Research Papers
Cascading chemiresistive paper-based enzymatic biosensor for urea detection
The conventional approach for diagnosing high risk metabolic disorders, such as chronic kidney disease (CKD), involves drawing a blood sample, which necessitates access to a centralized facility, making it undesirable for frequent urea monitoring. Alternative biological fluids, such as saliva, have demonstrated potential as non-invasive mediums for CKD monitoring due to the strong correlation between blood urea and salivary urea levels, indicating their suitability for point-of-care test kits. In this study, we present an innovative chemiresistive paper-based enzymatic sensor that utilizes a combination of urease and polystyrene sulfonate (PSS) to measure urea. This sensor detects urea over a broad concentration…
Long-Term Controlled Growth Factor Release Using Layer-by-Layer Assembly for the Development of In Vivo Tissue-Engineered Blood Vessels
The development of a well-designed tissue-engineered blood vessel (TEBV) still remains a challenge. In recent years, approaches in which the host response to implanted biomaterials is used to generate vascular constructs within the patient’s body have gained increasing interest. The delivery of growth factors to these in situ-engineered vascular grafts might enhance myofibroblast recruitment and the secretion of essential extracellular matrix proteins, thereby optimizing their functional properties. Layer-by-layer (LbL) coating has emerged as an innovative technology for the controlled delivery of growth factors in tissue engineering applications. In this study, we combined the use of surface-etched polymeric rods with LbL…