3D Bioplotter Research Papers

Two high-compliance β-Ti alloys – Ti–12Nb–12Zr–12Sn and Ti–6Nb–6Mo–12Zr–12Sn (wt.%) – are manufactured into microlattices via 3D ink-extrusion printing of elemental and hydride powders, followed by sintering and solutionizing at 1400 °C. This study reveals that the formation of “oxygen-rich walls” plays a critical role in triggering embrittlement with intragranular cracking. In compression tests, the Ti–12Nb–12Zr–12Sn microlattices exhibit high compliance (2–6 GPa) but low collapse strength (25–115 MPa) along with semi-brittle behavior, even though stress-induced α” martensite is triggered: stress-strain serrations are explained by the oxygen-rich walls decorated with α plates and athermal ω nanostructures. Nanostructures along these walls are caused by the formation…

A variety of different approaches have been employed to enable implantation of electronic medical microdevices. A novel method of producing low-cost, rapidly fabricated implantable enclosures from biocompatible silicone is presented in this paper. This method utilises 3D computer-aided design software to design and model the enclosures prior to fabrication. The enclosures are then fabricated through additive manufacturing from biocompatible silicone using a 3D bioprinter. In this paper, four different implantable enclosure designs are presented. A prototyping stage with three different prototypes is described, these prototype enclosures are then evaluated through submersion and operation tests. A final design is developed in…

A number of methods have been used to make electronic medical microdevices biocompatible. This paper presents a novel approach for design and fabrication of biocompatible silicone enclosures for implantable medical microdevices. The approach involves design and formation of a 3D model of the enclosure using a computer-aided design software tool, followed by 3D printing of the enclosures using a bioplotter. Three different implantable enclosure designs are presented. The fabrication of the three enclosures is given. An evaluation of the suitability of the enclosures for implantation of a deep brain stimulation microdevice is discussed through submersion and operation tests. The evaluation…