3D Bioplotter Research Papers

Displaying all papers by H. Huang (1 results)

Multi-compartment Organ-on-a-Chip Based on Electrospun Nanofiber Membrane as In Vitro Jaundice Disease Model

Advanced Fiber Materials 2021 Volume 3, Pages 383–393

Organ-on-a-chip (OOC) is now becoming a potential alternative to the classical preclinical animal models, which reconstitutes in vitro the basic function of specific human tissues/organs and dynamically simulates physiological or pathological activities in tissue and organ level. Despite of the much progress achieved so far, there is still an urgent need to explore new biomaterials to construct a reliable and efficient tissue–tissue interface and a general fabrication strategy to expand from single-organ OOC to multi-organ OOC in an easy manner. In this paper, we propose a novel strategy to prepare double-compartment organ-on-a-chip (DC-OOC) using electrospun poly(l-lactic acid)/collagen I (PLLA/Col I)…