3D Bioplotter Research Papers

Displaying all papers about Antithrombotic (1 results)

3D toro-poloidal implantable device for the controlled delivery of rivaroxaban

University of the Witwatersrand 2023 Thesis
S. V. Mavuso

Implantable drug delivery devices offer many benefits over other routes of drug delivery. Most significantly, the potential of reducing systematic side-effects and improving patient compliance as drugs are delivered in lesser doses over an extended period. The present work was focused on designing a novel polymeric blend through a judicious combination of polymers. Polymeric material was used for the fabrication of implantable drug delivery devices (IDDDs) with varying geometrical considerations viz. torus and cylinder for the controlled delivery of a model antithrombotic agent, rivaroxaban (RXB). RXB is an antithrombotic drug used primarily for the prevention of stroke and systemic embolism…