3D Bioplotter Research Papers

Current techniques for assessment of critical quality attributes (CQA) of engineered tissues primarily utilize histological and biochemical assays, which are predominantly offline, destructive, and time- and resource-intensive. To accelerate the translation of tissue engineering technologies from laboratories to scaled up/out manufacturing, advances in biofabrication processes need to be supplemented with appropriate nondestructive, inline quality assessment techniques. Accordingly, this dissertation focuses on dielectric spectroscopy (DS), which utilizes the responses of living cells to alternating electric fields to interpret their CQA in real time. Whereas majority of DS literature and current applications pertain to cells in suspension, this work investigates DS of…